Pigmented Contact Dermatitis Due to After Shave Lotion / 대한피부과학회지

Pigmented contact dermatitis is characterized by a dark brown pigmentation that results from repeated exposure to small amounts of contact allergen. Histopathologic findings are liquefactive degeneration of the basal layer cells and melanophages in the upper dermis. We report a case of a 73-year-old man with dark brownish mottled hyperpigmented patches on the both cheeks and forehead. Patch tests were positive to isoeugenol, benzyl salicylate and after shave lotion. After shave lotion that the patient used maybe contain these fragrances. Improvement was seen 3 months after ceasing the use of after shave lotion.

Two Cases of Generalized Granuloma Annulare Treated with PUVA / 대한피부과학회지

Granuloma annulare is a benign granulomatous disease which has an unknown etiology and it is represented by typical annular lesions. Recently various therapeutic modalities have been suggested such as intralesional injections of steroid, chloroquine, dapsone, surgical excision and so on. But any satisfactory result has not been reported yet. In the first case, a 65 year-old-man, Polycyclic, erythematous patches with raised edges were noted on the upper arm spreading to the trunk and both lower extremities for the past 3 years. In the second case, a 63-year-old man, numerous match-head sized skin-colored papules were detected on the sun exposed area such as both shoulders, upper extremities and hands dorsum for the past 3 months. On the histological examination of back, hands dorsum respectively, incomplete degeneration of collagen bundles surrounded by lymphocytes, histiocytes in a palisade pattern and a few giant cells were found in the dermis. Two patients were treated with systemic PUVA, one for 2 months and the other, 4 months.

Two Cases of Generalized Granuloma Annulare Treated with PUVA / 대한피부과학회지

Granuloma annulare is a benign granulomatous disease which has an unknown etiology and it is represented by typical annular lesions. Recently various therapeutic modalities have been suggested such as intralesional injections of steroid, chloroquine, dapsone, surgical excision and so on. But any satisfactory result has not been reported yet. In the first case, a 65 year-old-man, Polycyclic, erythematous patches with raised edges were noted on the upper arm spreading to the trunk and both lower extremities for the past 3 years. In the second case, a 63-year-old man, numerous match-head sized skin-colored papules were detected on the sun exposed area such as both shoulders, upper extremities and hands dorsum for the past 3 months. On the histological examination of back, hands dorsum respectively, incomplete degeneration of collagen bundles surrounded by lymphocytes, histiocytes in a palisade pattern and a few giant cells were found in the dermis. Two patients were treated with systemic PUVA, one for 2 months and the other, 4 months.

A Case of Nodular Pseudosarcomatous Fasciitis / 대한피부과학회지

Nodular pseudosarcomatous fasciitis is characterized as rapidly growing benign tumor with microscopically resembling sarcoma in the upper extremities, especially forearms. Most lesions are located in the subcutaneous tissue, although these may also be found intramuscularly, with the involvement of the adjacent fascia or periosteum and dermis.

A Case of Churg-Strauss Syndrome With Acute Glomerulonephritis / 대한피부과학회지

Churg-Strauss syndrome is a rare systemic vasculitis diagnosed by the presence of any four or more of six criteria which include asthma, eosinophilia>10%, mono- or poly-neuropathy, nonfixed pulmonary infiltrate, paranasal sinus abnormality, extravascular eosinophils. In a 65 year-old-woman, multiple purpura and crusted ulcer with central necrosis were developed on the both extremities and buttocks 1 month ago. She has been suffered from asthma, sinusitis and recurrent pneumonia since ten years ago Laboratory findings showed hematuria, hypereosinophilia and hyperIgE. On the histological examination of ulcerative nodule on the right leg, leukocytoclastic vasculitis and many neutrophils and eosinophils around the cutaneous vessels were seen and the other findings were fibrinoid necrosis and thickening of vessels wall without eosinophilic granulomatous changes. Renal biopsy showed focal segmental glomerulonephritis and sclerosing nephritis. We report a rare case of Churg-Strauss syndrome with acute glomerulonephritis.

Patch Test of Cosmetic Cleansers for the Determining Optimum Concentration / 대한피부과학회지

BACKGROUND: Cosmetic cleansers are most widely used to remove makeup and sometimes cause allergic or irritation contact dermatitis. We can patch test soaps or shampoos as 2% concentration, but cleansers have been not determined for the concentration by patch test yet. OBJECTIVE: The objectives of this study were to determine the concentration of cosmetic cleansers for patch test. METHODS: The skin responses to patch testing with variable cleansers in different concentrations were measured by visual scoring, spectrometer, evaporimeter and corneometer. RESULTS: The results of the studies were summarized as follows; 1. The cream type and lotion type cleansers showed no skin responses. 2. The skin response of foam type cleansers showed that the one had statistical significance between 2% and 5%, and the other had 5% and 10% concentration. 3. The skin response of gel type cleansers showed statistical significance between 5% and 10% concentration. 4. Through correlation analysis, we found that the evaluation of the evaporimeter or corneometer were not related to the visual measurement. CONCLUSIONS: We suggest that cosmetic cleansers of water, lotion and cream type can be tested as is(100%), and foam type cleansers with 2%, and gel type should be tested with 5% concentration.

A Case of Symptomatic Zinc Deficiency due to Total Parenteral Nutrition / 대한피부과학회지

Symptomatic Zinc Deficiency occurs due to decreased supplimentation, increased consumption, and decreased bowel absorption of the zinc. We report the typical case of symptomatic zinc deficiency in a patient who received total parenteral nutrition for about 4 weeks due to chronic diarrhea. And after supplementation with oral zinc sulfate, the diarrhea stopped in a day and skin lesions disappeared completely within a week.